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Rajarethinam Vitamin B 12 Deficiency and Depression in the Elderly: Review and Case Report. Journal of Clinical Psychiatry, 2009, doi: 10.4088/PCC.08100707

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Iron can directly produce excess ROS in cells through Fenton reaction and increase cellular oxidative damage

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Nevertheless, some heavier elements in these groups are subject to microbially-mediated biotransformation, and microbes may play a role in their biogeochemical cycling