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Moreover, many other oxysterols can participate in cholesterol metabolism and the levels of these were increased in the brains of late AD patients, including 25-hydroxycholesterol (25-OHC), 7-ketocholesterol (7-K), 7-hydroxycholesterol (7-OH), 5,6-epoxycholesterol (-epoxy), 5,6-epoxycholesterol (-epoxy), 4-hydroxycholesterol (4-OH), and 4-hydroxycholesterol (4-OH