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By studying how the local microbiome affects immunity at remote locations and how the gut microbiota affects other organs, scientists have coined terms such as the gut-brain axis and the gut-lung axis

As absorption is reduced, body stores become low and a deficiency occurs Underlying diseases most commonly include: IBD (inflammatory bowel disease) Intestinal cancer (especially small cell lymphoma) Liver disease Pancreatitis and other pancreatic diseases Symptoms of low B12 levels Typically found in middle-aged or older cats that present with: Weight loss Diarrhea Vomiting Anorexia Thickened intestines In humans, B12 deficiency may also be associated with dementia, cardiovascular disease, and a certain type of anemia, although these are not specifically recognized problems in cats

Medina PJ, Sipols JM, George JN (2001) Drug-associated thrombotic thrombocytopenic purpura-hemolytic uremic syndrome

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Those schedule choices were coordinated with additional efficiency measures, including high-performance lighting, outside air units that support HVAC efficiency and indoor air quality, and a hybrid mechanical system