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Importantly, our cell culture observations were corroborated by our results obtained in animal studies, suggesting that increased hepatic protein S -glutathionylation contributes to NAFLD pathogenesis via suppression of the NF-B signaling pathway in hepatocytes

The effects of NTZ were compared to those of the standard antioxidant, N-acetyl cysteine (NAC), as a well-documented hepatoprotective agent known to inhibit ER stress, and to those of 4-phenyl butyrate (4-PBA), a standard ER stress inhibitor (Soliman et al., 2019)

elegans) , and the Drosophila homolog CncC, in determining longevity was recently shown

Fujii, T

Acknowledgments The authors would like to thank the Core Facilities Sharing Platform for Life and Environment Sciences of Shandong University, including Cheng-Jia Zhang and Nan-Nan Dong for providing the bacteriological incubator and Zhi-Feng Li for RT-qPCR instruction