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An imbalance between cellular oxidative and antioxidant systems, along with accumulation of oxidative damage and downregulation of Bcl2, can reduce the anti-apoptotic capacity of melanocytes, ultimately leading to hair greying [162]

Financing Although 70% of PCs have national budget lines for HBV testing and treatment, more PC funds are needed to scale up programs

While European nations set permitted thresholds for inorganic As at 0.15 mg/kg in polished rice [19,20,21]

Similarly, the flavonoid calycosin, which also possesses antioxidant and anti-inflammatory properties, prevents high glucose-induced cell ferroptotic damage by upregulating the GSH/GPX4 pathway in human renal proximal tubular epithelial cells (HK-2 cells), reducing LPO, and inhibiting the expression of nuclear receptor coactivator 4 (NCOA4) (141)