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MB: Conceptualization, Formal Analysis, Writing review and editing

The lipid metabolomics analysis highlighted the PPARa signaling pathway as a key focus of our investigation, we further demonstrated that PPARa participates in TSCI-induced neuronal ferroptosis, because the PPARa agonist Fenofibrate significantly reduced the lipid peroxidation level and thus promoted neuronal survival as well as the axon

The supernatants collected from the liver and kidney were kept separately for assays of antioxidant activities, lipid peroxidation, and apoptotic enzyme activities

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Long-Acting Amylin Agonist GUB014295 Gubra A/S (Hrsholm, Denmark), a biotech company specialized in pre-clinical contract research, initiated a phase 1 clinical trial (NCT06144684) to investigate the safety, tolerability and pharmacological properties of GUB014295 (GUBamy), a long-acting OW SC amylin agonist, in healthy volunteers [117]