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PERK phosphorylates eIF2 to rapidly inhibit general protein translation to reduce the stress load and activate ATF4, which promotes chaperone production and stress response genes [2123]

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[DOI] [PMC free article] [PubMed] [Google Scholar] [106].Randall LM, Ferrer-Sueta G, Denicola A, Peroxiredoxins as preferential targets in H 2 O 2 -induced signaling, Methods Enzymol

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