glutathione reaction product system enhancement for cardiac protection: pharmacological options against oxidative stress and ferroptosis GLUTATHIONE SYNTHESIS - PMC

Gleeson D, Lelu-Walter M-A, Parkinson M

Increased ROS also activate nuclear factor kappa B (NF-B), which drives the expression of pro-inflammatory cytokines and adhesion molecules, contributing to renal dysfunction [134]

Genistein protects against doxorubicin-induced cardiotoxicity through Nrf-2/HO-1 signaling in mice model

J Endocrinol Invest

the most important of which is through tyrosinase inhibition

The complex pathophysiology of NASH mandates a holistic approach to treating patients, focusing not only on liver histology but also cardiovascular risk and glycemic control, which has proven to be a high bar ( Table 1 )