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However, it should be noted that among the amino acids present in breast milk, circadian fluctuations are observed particularly in tryptophan, with levels rising at night, peaking in the early morning hours, and reaching their lowest levels in the afternoon [7, 23]

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10.1002/ijc.28975 34

A previous RCT investigated the effect of pyridoxine or placebo on migraine patients

Targeting IKK/NF-kappaB pathway reduces infiltration of inflammatory cells and apoptosis after spinal cord injury in rats

It is reported that some ascorbate-specific transport carriers ensure its diffusion to stroma from the cell cytosol (Foyer and Lelandais, 1996