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Studies indicate that the prevalence of four principal microbial phylaFirmicutes, Actinobacteria, Bacteroidetes, and Proteobacteriacorrelates with host bone mass (72)utilizing 16S rRNA sequencing demonstrated disparities in the GM between OP patients with osteoporotic fractures and healthy controls

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For example, consuming processed meats containing nitrates and nitrites, which are converted into nitric oxide (NO) in the body, can cause vasodilation, potentially altering cerebral blood flow and triggering migraines (Gonzalez et al., 2016)

Imbalances within the microbial community can either positively or negatively affect the integration of the gut and skin ( Supplementary Figure 1A )

Eskelinen MH, Kivipelto M (2010) Caffeine as a protective factor in dementia and Alzheimers disease

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