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Presenilin protein mutations are to blame for the bulk of FAD instances

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further, the overexpression of occludin alleviates the cytokine-induced increase in gut permeability 57

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Their structure comprises a conjugated sp 2 carbon core and an sp 3 -hybridized surface enriched with oxygen-containing groups such as hydroxyl, carbonyl, and carboxyl moieties [Figure 1A)