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Despite the effectiveness of phytochemicals in reducing the severity of AFs side effects, there have been no comprehensive clinical studies to use these herbaceous metabolites for detoxifying of AFs

Methionine S-adenosyl methionine (SAM), a methionine metabolite, may interact with opioids, antipsychotics, amphetamines, and antidepressants to cause an overabundance of serotonin to accumulate in the body