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Whats more, our health can also improve (or worsen) without an obvious trigger

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Accumulating evidence suggests that these interventions help restore gut microbial balance and promote a favorable intestinal microenvironment similar to that observed in healthy individuals [136,151]

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Nevertheless, several key observations in our model, including the reduced number of ciliated cells, the increase in secretory cells, and a loss of cellular resilience in IPF-derived phBECs, are consistent with reported epithelial alterations in IPF in vivo, supporting the value of our model as a meaningful platform for mechanistic investigation 71,72

[DOI] [PMC free article] [PubMed] [Google Scholar] 122.Fiorentino M., Sapone A., Senger S., Camhi S., Kadzielski S.M., Buie T.M., Kelly D.L., Cascella N., Fasano A