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Tamber SS, Bansal P, Sharma S, Singh RB, Sharma R (2023) Biomarkers of liver diseases

Furthermore, the link between astrocytic metabolism and neurodegeneration is gaining traction: during brain aging or degenerative processes, the efficiency of astrocyte-neuron metabolic couplingcritical for glutamate homeostasis via transporters like GLT-1 and GLASTdeclines, leading to reduced glutamate clearance, extracellular accumulation, and NMDA receptor-mediated excitotoxicity, which drives neuronal dysfunction

Youll age faster, your DNA will take more hits, and youll be at higher risk for illnesses including cancer, diabetes, Alzheimers, and heart disease (4)

PPT1 inhibition induced lysosomal lipid peroxidation (LLP), which led to lysosomal membrane permeabilization and cell death that could be reversed by the antioxidant N-acetylcysteine (NAC) but not by other lipid peroxidation antioxidants

Science 367 , 205210 (2020)

Taking more does not always mean better results, so we must follow recommended amounts