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Studies show a 1.5- to 3-fold increase in BDNF in the cortex and hippocampus after intranasal administration

Whole wounds of 6 mm in diameter were created within an ischaemic bicuspid flap on the back of each rat

Clin Chem 55:18521860 Ono K, Yamada M (2007) Vitamin A potently destabilizes preformed alpha-synuclein fibrils in vitro: implications for Lewy body diseases