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Sarsour, E

Administration of the ferroptosis inhibitors Fer-1 and DXZ significantly reduced mortality, whereas inhibitors of apoptosis, necrosis, and autophagy did not improve the condition of the mice [226]

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In Korea, many women use glutathione for skin health, as it improves skin tone, defends against oxidative stress (thus minimizing aging signs like wrinkles), stimulates collagen synthesis, and alleviates redness and inflammation for a calmer, healthier complexion

it can be enzymatically detoxified or it reacts with proteins, transition metals or carbon dioxide ( 2 O 2 can be removed by the action of glutathione peroxidase (GPx), catalase (CAT), or peroxiredoxin, all of which convert it to water and oxygen ( 2 O 2 encounters a transition metal such as divalent iron (Fe 2+ ), it is non-enzymatically converted to the highly reactive hydroxyl radical (OH)

These results suggest that miR-122 exerts a protective effect against the development of MASLD