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The kallikreinkinin system and protease-activated receptor signalling have been implicated in the progression of DKD

GnRH (gonadotropin-releasing hormone) agonists are synthetic hormones that stimulate the pituitary gland to release follicle-stimulating hormones (FSH) and luteinizing hormones (LH), which help the ovaries to function

Alternatively, a collection of naturally-occurring CDR sequences may be compared to generate consensus sequences so that amino acids used at a residue position frequently (i.e., in at least 5 percent of known CDR sequences) are incorporated into the synthetic CDRs at the corresponding position(s)

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Krugluger, W., Rohrbacher, W., Laciak, K., Moser, K., Moser, C, and Hugenneck J., Reorganization of hair follicles in human skin organ culture induced by cultured human follicle-derived cells