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Short-term clinical trial data from the Metabolic Pharmaceuticals program did not reveal serious adverse events at the doses tested orally

They address NAD+ depletion from opposite sides

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ED is commonly managed with first-line treatments, including phosphodiesterase type 5 (PDE5) inhibitors (sildenafil, tadalafil, and vardenafil), which enhance nitric oxide-mediated vasodilation to facilitate erections and are effective in many diabetes patients