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Statistical analysis was performed using Graphpad prism for windows

Specifically, curcumin has been shown to mediate the covalent modification of the active site cysteine (Cys) 496 and selenocysteine (Sec) 497 residues in TrxR, subsequently destroying TrxR reduction activity, a process that is irreversible and further leads to dramatic pro-oxidant effects, the induction of NOX activity, and the production of ROS [97]

The impact of oxidative stress in male infertility

Antioxidant activity of a sample was expressed in terms of micromole equivalents of trolox

Involvement of the endocannabinoid system in drug addiction

The deaths are the result of a process begun decades earlier