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302 Interestingly, Sig-1R stabilizes IRE1 and enhances the endonuclease activity required for the UPR, which, in turn, prevents PERK signaling and regulates Ca 2+ signaling

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Furthermore, ATF4 synergizes with HIF-1 under hypoxic conditions in infantile hemangioma (IH) proliferative phases, driving M2 macrophage infiltration to fuel lesion expansion (183)

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doi: 10.3390/cancers15010087 25

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The genotypes and phenotypes of missense mutations in the proline domain of the p53 protein

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On the contrary, commensal bacterial communities, particularly probiotics, emerge as key contributors to redox homeostasis (107)

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