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A single D208N mutation introduces PDH activity in a spirochaetes TyrA a To test if the acidic residue at the corresponding 222 position in spirochaetes SsTyrA a is involved in its substrate specificity, the D208N mutation that converts the active site acidic residue into a non-acidic residue was introduced in SsTyrA

Evidence of myocardial lipid peroxidation in a patient with COVID-19 suggests ferroptosis may contribute to the cardiac damage associated with the virus (174)

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Cloudiness indicates protein aggregation or bacterial contamination, both of which render the peptide unsafe and ineffective