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The p53/p21 and p16/Rb (retinoblastoma) axes are the two central signaling pathways involved in senescence regulation

Molecular Weight: 1419.556 g/mol

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While our analyses controlled for key time-varying confounders (temporal order of the antipsychotic, schizophrenia-related hospitalization or emergency room visits within 3 months before the starting date of the subperiod, etc.), we cannot rule out the possibility of unobserved time-varying confounders (e.g., changes in non-psychiatric or psychiatric symptoms and severity, consumption of co-medications) that our analyses did not control for and could still bias our study results