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Pubmed Central PMCID: PMC3656452

In SURMOUNT-1 (Phase 3), tirzepatide at 15 mg produced 22.5% body weight loss at 72 weeks

We therefore created novel ovarian tumour cell line models in which GSTP1 expression is stably deleted, to investigate whether differential GSTP1 expression directly influenced chemosensitivity to platinum drugs, and to other drugs routinely used in the treatment of ovarian cancer patients