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Abstract Glycine N-methyltransferase (GNMT) exerts a pivotal role in the methionine cycle and, consequently, contributes to the control of methylation reactions, and purine and pyrimidine synthesis

66 In contrast, pharmacologic inhibition of FAO with etomoxir or ranolazine inhibited cancer cell proliferation and sensitized human leukemia cells to apoptosis induced by ABT-737, a molecule that released proapoptotic Bcl-2 proteins such as Bak from antiapoptotic family members, suggesting that CTP1 can antagonize Bcl-2-induced apoptosis

Pathogenic mechanism of the FIG4 mutation responsible for Charcot-Marie-Tooth disease CMT4J

Melatonin ameliorates oxidative stress and reproductive toxicity induced by cyclophosphamide in male mice

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