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If the maximum recorded temperature exceeds 8C or the minimum drops below 1C (risking freeze damage), adjust the refrigerator setting or relocate vials to a more stable zone

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Hepatic immune cells, TAMs, and macrophages in the non-tumor regions (non-TAMs) were isolated using CD45 + and F4/80 + magnetic beads, followed by analysis of mitochondrial DNA (mtDNA), cellular dNTP levels, RNAseq, western blot, and flow cytometry