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Name: l carnitine effects on brain L-Carnitine in the Treatment of Psychiatric and Neurological Manifestations: A Systematic Review L-Carnitine in the Treatment of
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425,426 Aging, smoking, cardiovascular disease, obesity, high-fat diet, hypertension, excessive sun exposure, and other factors can induce mtDNA damage and increase ROS production, resulting in mitochondrial dysfunction and ultimately leading to RPE cell damage

This estrogen action becomes especially relevant under chronic inflammation conditions, where perpetuation of microglial proinflammatory status induce neuronal damage