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If you know you carry the MTHFR mutation, you may require higher doses of methylfolate

Funding This study was supported by the National Natural Science Foundation of China (82272408)

There are liquid supplements just for people with kidney disease, but you must check with your healthcare provider before taking them, especially if you are on a fluid restriction

doi:10.1016/j.ejvs.2021.11.016 Drame M, Godaert L

2024;112 doi: 10.1016/j.compbiolchem.2024.108153

Significantly more CagriSema participants achieved clinically meaningful weight loss thresholds of 5%, 10%, 15%, and 20% compared to placebo at all timepoints assessed