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Data extraction and quality appraisal was completed by two reviewers

Indian J Psychiatr

A 2024 human clinical study found oral fisetin reduced senescent peripheral blood mononuclear cells and lowered SASP inflammatory markers

Once largely confined to clinical research and discussions around antioxidants, it now appears across brightening serums, glow creams, and tone-correcting formulations, frequently positioned as the secret behind clearer, more luminous, even-toned skin