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The complex world of WNT receptor signalling

Saoura, M

We found that a majority of intratumoral CAR T cells expressed markers of T cell activation but, unexpectedly, constituted 5% of all T cells within the TME 5 days or more after therapy

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Suppressing this cholesterol response was further shown to sensitize AML cells to drug treatment, suggesting that MVA pathway inhibition by statins may improve the efficacy of conventional chemotherapy (203, 218)

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