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Zinc supplementation can cause a copper deficiency

Onychomycosis is caused by 3 main classes of organisms: dermatophytes (fungi that infect hair, skin, and nails and feed on nail tissue), yeasts, and nondermatophyte molds

Semin Nephrol (2010) 30(2):16476

Furthermore, 8-oxo-dG DNA glycosylase (OGG1) recruited to these lesions interacts with TET1 that can trigger active DNA demethylation by BER (Zhou et al., 2016)