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Clinical experience in cell-based therapeutics: intervention and outcome

Here, we employed comparative global metabolomics to demonstrate that metabolism of the antioxidant glutathione (GSH) is inextricably linked to redox-active processes that facilitate melanin production, and that genetic perturbations in GSH biosynthesis affect fungal growth and virulence in a murine model of cryptococcosis

NFE2L2 Similarly, the NFE2L2 pathway is another crucial player in regulating ferroptosis

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doi: 10.1016/j.micpath.2017.12.034 81 MurakamiH.OgawaraH.HiroshiH

This section will take a closer look at the impact of low, moderate, and high BAC levels