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Clinical findings In 1971, Folkman [1] proposed that new blood vessel formation (angiogenesis) is necessary for the progression of solid tumours beyond a size of a few millimetres cube and that blocking angiogenesis in tumours might be an effective means of maintaining or inducing dormancy and preventing metastasis

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In the present study, by constructing in vitro and in vivo AKI models, with ferroptosis as an entry point, the mechanism of RGSH in ameliorating AKI was evaluated