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After utilizing disulfiram (DFS) to treat GBM cells, the expression of GPX4 was reduced, which induced the production of ROS and increased the sensitivity of GBM cells to ferroptosis [63]

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Western blot analysis confirmed robust DHODH downregulation in shDHODH-transduced A431 cells (Fig

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[DOI] [PMC free article] [PubMed] [Google Scholar] 377

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Proceedings of the National Academy of Sciences, 85 (9), 31753179

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