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Funding The authors acknowledge the financial support provided by CSIR (Council of Scientific and Industrial Research), New Delhi and UGC-SAP, New Delhi

Glutamine is imported into cancer cells via multiple transporters, including the Na + -dependent transporters, system ASC (alanine/serine/cysteine-preferring) that function as obligatory exchangers, and the Na + -coupled neutral amino acid transporters (SNATs), which belong to the SLC38 superfamily (Cha et al., 2018)

This hyperpigmentation typically diminished in follow-ups after the study period, but it represents a temporary concern requiring management

Glucosamine is a natural compound found in the human body, predominantly in our joints

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Meuleman C, Vandenabeele B, Fieuws S, Spiessens C, Timmerman D, DHooghe T