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The NLRP3 inflammasome is a molecule associated with epilepsy, which can be triggered by ROS (151,152)

J Biol Chem 281: 1042010430 Lee DW, Kaur D, Chinta SJ, Rajagopalan S, Andersen JK (2009) A disruption in ironsulfur center biogenesis via inhibition of mitochondrial dithiol glutaredoxin 2 may contribute to mitochondrial and cellular iron dysregulation in mammalian glutathionedepleted dopaminergic cells: implications for Parkinsons disease

doi: 10.7150/thno.37574 34 GuoJWangJFanJZhangYDongWChenC-P