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Safety and efficacy of fecal microbiota transplantation (Fmt) as a modern adjuvant therapy in various diseases and disorders: A comprehensive literature review

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105 STRO-002 has been evaluated in several trials (e.g., NCT03748186, NCT05200364) and more recently has advanced to late-stage clinical trials (e.g., NCT06555263, NCT05870748)

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It not only serves as a site for the absorption of food nutrients and microbial metabolites, but also acts as a barrier to prevent microbial invasion of the tissues and moderates the inflammatory response to the myriad of contents in the intestinal lumen

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doi: 10.1016/j.fertnstert.2014.04.017 75 LazarosLAXitaNVChatzikyriakidouALKaponisAIGrigoriadisNGHatziEGet al

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Targeting purine synthesis in ASS1-expressing tumors enhances the response to immune checkpoint inhibitors

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