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2.4 Site-specific conjugation To avoid the heterogeneous drug-to-antibody ratios (DAR) of stochastic lysine/cysteine conjugation, precision engineering is essential for both Onc-ADCs and ID-ADCs ( 2.5 Structural biology and computational design Structural biology provides the atomic-resolution framework necessary for rational ID-ADC design

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The central role of thiol (SH) and selenol (SeH) groups as the generic targets of electrophile mercury forms and the need of new in silico tools to guide the future biological researches will be commented

I have notice a lot of test requests do not follow, and I will now go see if the new guideline covers the remaining questions, and gets us all doing the same

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