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It is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for type 2 diabetes (Mounjaro) and chronic weight management (Zepbound)

(2017) 171:628641.e26

On the other hand, fluvoxamine only increases serotonin, but the drug possesses a unique anti-inflammatory property to ease fatigue

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Further, the authors provide supportive orthogonal data from in vivo mouse models, ex vivo analysis from blood of healthy donors, and pre-on proteomic analysis from patients treated with ICI