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The same person might use one protocol for anti-aging and another for injury recovery

In: StatPearls

In estrogen biology, GSTM1 and GSTT1 serve a specific and critical function: they conjugate the reactive quinone metabolites produced when catechol estrogens particularly 4-OHE2 (4-hydroxyestradiol) are not rapidly methylated by COMT or sulfated by SULT1A1 and instead undergo further oxidation: The oxidation cascade: CYP1B1 converts estradiol to 4-OHE2 if COMT and SULT1A1 cannot clear 4-OHE2 quickly, one-electron oxidation produces 4-OHE2 semiquinone two-electron oxidation produces 4-OHE2 quinone (4-OHE2-Q)

Matuszyk et al., 2021)

Common Side Effects Injection-site reactions: Discomfort, redness or soreness at the site can occur

These substances are often substances produced by the body (metabolites) that cannot be removed properly due to the impaired function of the kidneys