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The modifier subunit of Drosophila glutamate-cysteine ligase regulates catalytic activity by Covalent and noncovalent interactions and influences glutathione homeostasis in vivo

Raninga, P

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In its open, inactive form, the active site structure forms a loop while one subunit adopts an asymmetric open conformation and the other adopts a quasi-open conformation

Fatty acid synthesis primarily depends on key rate-limiting enzymes: ATP-citrate lyase (ACLY), ACC, and FASN

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