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Taking L-carnitine by mouth or intravenously (by IV) seems to improve symptoms and increase exercise ability in people with heart failure

L -Carnitine and the recovery from exhaustive endurance exercise: a randomised, double-blind, placebo-controlled trial

First, it allows each participant to act as their control, minimizing individual variability's impact on baseline performance

In clinical research, supplementation enhanced high-intensity exercise capacity, improved repeated sprint performance, and delayed fatigue

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The next day, the suspensions were centrifuged at 8,500 g for 5 min at 4C, and the supernatants were removed