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With respect to ulcerative colitis (UC), (Malik et al., 2018) demonstrated that ERCs exert anti-inflammatory effects by rebalancing cytokine profilesreducing IL-2 and TNF- while increasing IL-4 and IL-10 levels

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doi: 10.3389/fimmu.2024.1500676 88 MornGUbertiBQuirogaJ

Rampanelli, E

Critically, PBMC from multiple sclerosis patients exhibit significantly lower 3-MST expression compared to healthy controls, with 3-MST levels negatively correlating with pro-inflammatory factors (142), suggesting endogenous H 2 S deficiency promotes autoimmune pathology by weakening DC tolerogenic programs

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