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Despite its therapeutic potential, the clinical translation of OA is hindered by poor aqueous solubility, limited cutaneous permeation, and rapid systemic clearance, which compromise bioavailability in topical applications [13]

Other studies investigated the two mechanisms of action of high-dose sodium selenite and selenium-containing chrysin (SeChry) in ovarian cancer (105)

doi:10.1038/nature13198 PubMed: 24717514 Pissios P

Generalizing predictions to unseen sequencing profiles via deep generative models

Activation of NF2 can promote the downregulation of E3 ubiquitin ligase CRL4 DCAF1 , suppress Lats1/2 degradation in the hippocampal pathway, thereby promote YAP phosphorylation [227]

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