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The elevated lactate levels observed in the brains of ME/CFS patients have important implications for understanding the pathophysiology (Natelson et al., 2017)

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Lactobacillus brevis G-101 ameliorates colitis in mice by inhibiting NF-B, MAPK and AKT pathways and by polarizing M1 macrophages to M2-like macrophages

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The HPA axis initiates a response in times of stress, stopping the activity through negative feedback, engaging the hippocampus and the paraventricular nucleus of the hypothalamus

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