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[69] In mice [70] and in rats [71] contextual fear conditioning, within 124 hours, it is associated with altered methylations of several thousand DNA cytosines in genes of hippocampus neurons

Among them, a key focus has been given to curcumin for its anti-cancer, anti-inflammatory, antibacterial, and antioxidant abilities

Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans: Psychotomimetic, perceptual, cognitive, and neuroendocrine responses