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Mutations in CDCA7 and HELLS cause immunodeficiencycentromeric instabilityfacial anomalies syndrome

doi: 10.2147/DDDT.S155110 516 LeiWTShihPCLiuSJLinCYYehTL

Tumor spheroid viability assay K1 cells were incubated to form spheroids (~ 7 days) in ultra-low binding 96-well plates for viability assay and in ultra-low binding 24-well plate for imaging with PI staining

Exclusion rates were kept to a minimum, with 13 patients across studies (13/196

Due to its mechanism of action and teratogenic effect, it is contraindicated in acute liver diseases and pregnancy (Depass and Weaver, 2017)

Cell Stem Cell 21 , 195208.e196 (2017)