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doi: 10.1002/cbdv.202402248 105 ZhaoJ-WZhaoW-YZhaoMYuL

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Recent studies employing various robust designs such as randomized, prospective, double-blind, placebo-controlled, crossover, comparative, non-randomized, contralateral, interventional, randomized parallel, longitudinal, and investigator-masked approacheshave highlighted the effectiveness of castor oil, derived from Ricinus communis , as a promising therapeutic option for managing a range of ocular surface diseases [328]

On activation CD4+ T cells differentiate into Th1 and Th17 subtypes, releasing cytokines like IL-17 and IFN- , these cytokines further stimulate neutrophils and macrophages, resulting in the onset of intestinal inflammation (63)

Aw YC, Brown AJ, Wu J-W, Yang H