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Importantly, the underlying cell death mechanism is triggered by CBS inhibition in HepG2 cells via ferroptosis, suggesting that CBS has a previously unreported function in this process

& Botstein, D

In fact, lipid peroxidation has been implicated in many disease states such as atherosclerosis, asthma, Parkinsons disease, kidney damage, preeclampsia, and others

[25]Ratz, Jodan D

Agarwal B, Swisher S, Ajani J, Kelly K, Fanning C, Komaki RR, Putnam JB, Abu-Hamda E, Molke KL, Walsh GL, Correa AM, Ho L, Liao Z, Lynch PM, Rice DC , Smythe WR, Stevens CW, Vaporciyan AA, Yao J, Roth JA