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Together, this study reveals the architecture and transport mechanism of OST/ and provides insights into the structurefunction relationships of this crucial transporter in BA homeostasis

Curr Pediatr Res 2023;27:1968-70

Ann Surg 229:713720 Hijikawa T, Kaibori M, Uchida Y et al (2008) Insulin-like growth factor 1 prevents liver injury through the inhibition of TNF-alpha and iNOS induction in D-galactosamine and LPS-treated rats

If a more potent GLP-1 effect with dual receptor engagement is the goal, switching to tirzepatide is the pharmacologically rational approach rather than combination