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And the biggest concern

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In vivo evaluations of these compounds have been conducted in diverse species, including mice, rats, non-human primates, and chickens, to investigate their effects on conditions such as addiction, aging, Alzheimers disease, autism, epilepsy, Huntingtons disease, ischemia, pain, Parkinsons disease, schizophrenia, and stroke (Cioffi and Guzzo 2016